Accession Number : AD1047896


Title :   Evaluation of the Physiological Challenges in Extreme Environments: Implications for Enhanced Training, Operational Performance and Sex-Specific Responses


Descriptive Note : Technical Report,30 Sep 2016,29 Sep 2017


Corporate Author : University of Montana Missoula United States


Personal Author(s) : Ruby, Brent C ; Slivka,Dustin


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/1047896.pdf


Report Date : 01 Oct 2017


Pagination or Media Count : 44


Abstract : The specific aim of the second segment of this project series was to determine the impacts of environmental conditions on specific markers of exercise training response and/or acclimation. Untrained males (n=36) served as study participants and were stratified across three training environments 1) control (20C, 30% RH), 2) heat (33C, 30% RH), or 3) cold (7C, 30% RH) environments. Daily training was prescribed for a period of 14 days. Following a controlled diet and exercise plan the day before and after overnight fast participants reported to the laboratory in the early morning hours. A muscle biopsy was obtained from the vastus lateralis (randomized, counter-balanced leg) before starting exercise (Pre) (days 1 and 15). Participants then exercised for 60 minutes at 60% of maximal aerobic capacity in one of the above-described environments. At the conclusion of the exercise trial, participants recovered (seated rest, under normal laboratory conditions) for four hours before a final muscle biopsy was taken (days 1 and 15). The additional four hours was necessary for the genes of interest to peak following exercise as previously described. Data was analyzed using a mixed design ANOVA with repeated measures between the training groups and across time, two-way 2 x 3 ANOVA (time x trial). A probability of type I error of less than 5 % was considered significant (p 0.05). At the time of this report, only a portion of the data has been analyzed. However, we have completed all study participant training and testing for this phase of the study (males).


Descriptors :   sex , exercise (physiology) , biopsy , Skeletal muscles , genes , physical fitness , mitochondria , temperature , ADAPTATION (PHYSIOLOGY)


Subject Categories : Medicine and Medical Research
      Anatomy and Physiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE