Accession Number : AD1046205

Title :   Mechanisms Underlying Stress Fracture and the Influence of Sex and Race/Ethnicity

Descriptive Note : Technical Report,30 Sep 2016,29 Sep 2017

Corporate Author : Massachusetts General Hospital Boston United States

Personal Author(s) : Bouxsein, Mary ; Popp,Kristin ; Caksa,Signe ; Rudolph,Sara

Full Text :

Report Date : 01 Oct 2017

Pagination or Media Count : 10

Abstract : This cross-sectional clinical study aims to examine potential mechanisms contributing to stress fracture risk. In particular, in Study 1, we will perform advanced skeletal imaging along with gait-assessments in subjects with history of a single vs multiple vs no prior stress fractures. In addition, in Aim 2, we will perform advanced imaging to delineate variation in skeletal features according to sex and race/ethnic-origin that may contribute or protect from stress fracture. To date, we have enrolled 21 subjects in Study 1 with an additional 9 subjects scheduled for their visit. Enrollment for both Aims is ongoing. Skeletal assessments are behind schedule due to the delay in installation of the second generation high-resolution peripheral quantitative computed tomography device at MGH. As studies are ongoing, we have not performed any data analyses.

Descriptors :   bone fractures , ETHNIC GROUPS , SEX , BIOMECHANICS , risk

Subject Categories : Medicine and Medical Research
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE