Accession Number : AD1046095


Title :   Mechanisms and Treatment of Deployment-Related Lung Injury: Repair of the Injured Epithelium


Descriptive Note : Technical Report,30 Sep 2016,29 Sep 2017


Corporate Author : National Jewish Health Denver United States


Personal Author(s) : Downey,Gregory P


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/1046095.pdf


Report Date : 01 Oct 2017


Pagination or Media Count : 42


Abstract : Since 2001, more than 2.8 million military personnel, DoD contractors, and US government and NGO employees supporting the war effort have been deployed to Southwest Asia. They have been exposed to a variety of hazardous conditions during deployment including direct physical lung injury from explosions as well as chronic exposures from inhalation of airborne PM and other harmful chemicals, including smoke from burn pits, sand, and geogenic dust containing potentially toxic metals such as titanium, cadmium, aluminum, and lead. Exposure to cigarette smoke is an additional risk factor for respiratory disease in these individuals. Consequently, mounting evidence demonstrates that military personnel returning from Southwest Asia have increased rates of respiratory symptoms compared to non-deployed military personnel.


Descriptors :   lung , wounds and injuries , veterans (military personnel) , RESPIRATORY SIGNS AND SYMPTOMS , Epithelium , PARTICULATE MATTER , LUNG DISEASES , asthma , fibrosis , gene expression , oxidants , ELECTRON MICROSCOPY , TOMOGRAPHY , high resolution , MASS SPECTROMETRY , epithelial cells , TOBACCO SMOKING , allergens , biological markers , inflammation , toxicity , EXPOSURE (PHYSIOLOGY)


Subject Categories : Medicine and Medical Research
      Anatomy and Physiology
      Genetic Engineering and Molecular Biology


Distribution Statement : APPROVED FOR PUBLIC RELEASE