Accession Number : AD1044797


Title :   Investigate the Role of Obesity in Ovarian Cancer Initiation and Progression


Descriptive Note : Technical Report,01 May 2015,30 Apr 2017


Corporate Author : Massachusetts Institute of Technology Cambridge United States


Personal Author(s) : Guarente, Leonard P ; Chalkiadaki,Angeliki


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/1044797.pdf


Report Date : 01 Jul 2017


Pagination or Media Count : 12


Abstract : During this funding period we focused on generating the mouse models that will enable achieve the goals of the proposed research. The aim of this project is to identify genes and pathways in ovarian stem cells and in transformed ovarian cells affected by obesity that lead to ovarian cancer initiation and progression.


Descriptors :   stem cells , Ovarian Cancer , OBESITY , inflammation , adipose tissue , genes , neoplasms , METASTASIS , DIET , gene expression


Subject Categories : Medicine and Medical Research
      Anatomy and Physiology
      Genetic Engineering and Molecular Biology


Distribution Statement : APPROVED FOR PUBLIC RELEASE