Accession Number : AD1044454


Title :   Plasmacytoma Infiltrating Leiomyoma in Multiple Myeloma


Descriptive Note : Conference Paper


Corporate Author : 59th MDW San Antonio United States


Personal Author(s) : Eden,Rina


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/1044454.pdf


Report Date : 19 Jan 2018


Pagination or Media Count : 2


Abstract : Extraosseus plasmacytoma is rare within the female genital tract. Here, we report the case of a 55 year-old female with a history of multiple myeloma who presented with a six month history of postmenopausal vaginal bleeding. Speculum exam revealed a mass protruding through the cervical canal highly suggestive of a prolapsed leiomyoma. After surgical resection, gross examination of the presumptive myomectomy specimen revealed a 4cm white, whorled mass with no areas of necrosis or hemorrhage. Microscopically, the mass was comprised of a well-circumscribed proliferation of smooth muscle diffusely effaced and expanded by a population of CD138+,lambda light chain-restricted plasma cells. We hypothesize that a preexisting submucosal leiomyoma became colonized by neoplastic plasma cells with resultant expansion and protrusion of the leiomyoma through the cervical canal. This case highlights a rare presentation of an extraosseous plasmacytoma within the female genital tract and to our knowledge is the first reported case of a plasmacytoma involving a leiomyoma.


Descriptors :   GENITAL DISEASES , females , GYNECOLOGY , myeloma , neoplasms


Subject Categories : Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE