Accession Number : AD1043107


Title :   Spinal Cord Swelling and Alterations in Hydrostatic Pressure After Acute Injury


Descriptive Note : Technical Report,30 Sep 2016,29 Sep 2017


Corporate Author : University of British Columbia, ICORD Vancouver, BC Canada


Personal Author(s) : Kwon, Brian K


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/1043107.pdf


Report Date : 01 Oct 2017


Pagination or Media Count : 76


Abstract : In year 3 of our grant, we conducted a series of experiments evaluating the effects of duraplasty onintraparenchymal spinal cord oxygenation, blood flow, and pressure, downstream metabolic response, behavioral recovery as well as histological changes. We ended up repeating our 12-week behavioral recovery study because an earlier study that we performed showed a tremendous (and frankly, amazing) improvement in locomotor function in the duraplasty-treated animals.


Descriptors :   SPINAL INJURIES , spinal cord , inflammation , Hydrostatic Pressure , CEREBRAL EDEMA , LOCOMOTION , physiological effects


Subject Categories : Anatomy and Physiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE