Accession Number : AD1038324


Title :   Follow-up Evaluation of Air Force Blood Donors Screening Positive for Chagas Disease


Descriptive Note : Conference Paper


Corporate Author : 59th Medical Wing San Antonio United States


Personal Author(s) : Marcus ,Joseph


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/1038324.pdf


Report Date : 27 Aug 2017


Pagination or Media Count : 6


Abstract : Background: Human Chagas disease is caused by the protozoan parasite Trypanosoma cruzi, is endemic to South Texas, and has significant morbidity and mortality related to cardiac toxicity. Consistent with national guidance from the FDA Blood Products Advisory Committee, the Joint Base San Antonio-Lackland blood bank screens all first-time blood donors for T. cruzi infection, currently with a chemiluminescent immunoassay. Although there is a published, standardized approach for diagnosis and evaluation of Chagas disease in the United States, local adherence to this approach has not been studied. Methods: A retrospective chart review was performed on all persons who screened positive for T. cruzion blood donation at Joint Base San Antonio-Lackland from 2014-2016. Charts were reviewed to determine frequency and results of confirmatory testing. Chagas disease was considered confirmed on the basis of positive EIA and TESA testing from the CDC and/or two different positive serologic tests. Among those with diagnosed diseases, charts were further examined to review whether patients underwent the recommended workup of history and physical, EKG, and 30 second rhythm strip; outcomes of these evaluations were ascertained.


Descriptors :   medical research , military medicine , blood donors , blood diseases , medical screening , toxicity , parasitic diseases


Subject Categories : Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE