Accession Number : AD1034592


Title :   Skeletal Muscle Hypertrophy and Cardiometabolic Benefits after Spinal Cord Injury


Descriptive Note : Technical Report,30 Sep 2015,29 Sep 2016


Corporate Author : McGuire Research Institute, Inc RICHMOND United States


Personal Author(s) : Gorgey,Ashraf


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/1034592.pdf


Report Date : 01 Oct 2016


Pagination or Media Count : 23


Abstract : Spinal cord injury is a devastating medical condition that increases ones risk for reduced aerobic fitness, glucose intolerance and insulin resistance due to increased body fat and relative inactivity. The purpose is to determine the impact of 12+12 weeks of NMES+FES-LEC on oxygen uptake, insulin sensitivity, glucose uptake, anabolic profile(Testosterone and IGF-1), basal metabolic rate (BMR). Four participants have completed the trial so far, two from the 12+12 weeks NMES+FES group and two from the 12+12 weeks control +FES group. Our preliminary data suggests that 12 weeks of NMES-induced resistance training prior to 12 weeks of FES improves metabolic profile, increases muscle size, and prevents an increase in leg fat mass. The NMES+FES group had a 13% increase in basal metabolic rate (BMR), while control +FES had a 13% decrease in BMR. Both groups experienced increased thigh muscle size with 24 weeks of training (8% for whole thigh and11% for knee extensors). Body composition analysis revealed that NMES +FES prevented the 13% increase in leg fat mass experienced by the control +FES


Descriptors :   spinal cord , spinal injuries , metabolism , glucose metabolism disorders , resistance


Subject Categories : Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE