Accession Number : AD1031683


Title :   A Multidisciplinary Approach to Study the Role of the Gut Microbiome in Relapsing and Progressive MS


Descriptive Note : Technical Report,30 Sep 2015,29 Sep 2016


Corporate Author : UNIVERSITY OF CALIFORNIA, SAN FRANCISCO San Francisco United States


Personal Author(s) : Baranzini,Sergio E


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/1031683.pdf


Report Date : 01 Oct 2016


Pagination or Media Count : 9


Abstract : While this contract was awarded in January 2015, it was finally approved in April 2016. Thus, all activities described in this Annual Report correspond to activities performed between April and September 2016.Despite these challenges, the project is now well underway and on track. A summary of accomplishments to date include: HRPO approval, Chart reviews to identify eligible subjects for this study at UCSF and Mt Sinai, Clinical evaluation and invitations to participate, mailing kits have been designed, prepared and started to being distributed to eligible participants, bacterial DNA is being purified from stool samples, quality control is being performed and Tob1/2D2 mice are currently being derived germ-free.These activities encompass most of the items described in the original SOW. Finally, while expenses have been posted according to the delayed start, the project is financially on track.


Descriptors :   medical research , biomedical research , immunology , genes , muscular diseases


Distribution Statement : APPROVED FOR PUBLIC RELEASE