Accession Number : AD1028465


Title :   Long-Term Follow-up of the Delayed Effects of Acute Radiation Exposure in Primates


Descriptive Note : Technical Report,30 Sep 2015,29 Sep 2016


Corporate Author : Wake Forest University Health Sciences Winston United States


Personal Author(s) : Cline,J M


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/1028465.pdf


Report Date : 01 Oct 2016


Pagination or Media Count : 100


Abstract : The overarching goal of this program is to explore our recent clinically relevant observations of DEARE in a unique cohort of non-human primates (NHP), termed the Radiation Survivor Cohort (RSC). This work consists of 4 projects: 1. Studies of type 2 diabetes mellitus (T2DM); 2. Radiation-induced heart disease (RIHD); 3. Chronic immune impairment with restriction of the antigenic response repertoire; and 4. Genomic and transcriptomic studies of the molecular pathogenesis of T2DM, RIHD, and immune impairment in the context of DEARE.


Descriptors :   RADIATION EFFECTS , exposure (physiology) , PRIMATES , diabetes mellitus , heart diseases , antigens , response (biology) , genome , PATHOGENESIS , biological markers , IMMUNE SYSTEM


Subject Categories : Radiobiology
      Anatomy and Physiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE