Accession Number : AD1028465

Title :   Long-Term Follow-up of the Delayed Effects of Acute Radiation Exposure in Primates

Descriptive Note : Technical Report,30 Sep 2015,29 Sep 2016

Corporate Author : Wake Forest University Health Sciences Winston United States

Personal Author(s) : Cline,J M

Full Text :

Report Date : 01 Oct 2016

Pagination or Media Count : 100

Abstract : The overarching goal of this program is to explore our recent clinically relevant observations of DEARE in a unique cohort of non-human primates (NHP), termed the Radiation Survivor Cohort (RSC). This work consists of 4 projects: 1. Studies of type 2 diabetes mellitus (T2DM); 2. Radiation-induced heart disease (RIHD); 3. Chronic immune impairment with restriction of the antigenic response repertoire; and 4. Genomic and transcriptomic studies of the molecular pathogenesis of T2DM, RIHD, and immune impairment in the context of DEARE.

Descriptors :   RADIATION EFFECTS , exposure (physiology) , PRIMATES , diabetes mellitus , heart diseases , antigens , response (biology) , genome , PATHOGENESIS , biological markers , IMMUNE SYSTEM

Subject Categories : Radiobiology
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE