Accession Number : AD1025708

Title :   A Highly Responsive Silicon Nanowire/Amplifier MOSFET Hybrid Biosensor

Descriptive Note : Journal Article

Corporate Author : Yale University New Haven United States

Personal Author(s) : Lee,Jieun ; Jang,Jaeman ; Choi,Bongsik ; Yoon,Jinsu ; Kim,Jee-Yeon ; Choi,Yang-Kyu ; Kim,Dong M ; Kim,Dae H ; Choi,Sung-Jin

Full Text :

Report Date : 21 Jul 2015

Pagination or Media Count : 6

Abstract : This study demonstrates a hybrid biosensor comprised of a silicon nanowire (SiNW) integrated with an amplifier MOSFET to improve the current response of field-effect-transistor (FET)-based biosensors. The hybrid biosensor is fabricated using conventional CMOS technology, which has the potential advantage of high density and low noise performance. The biosensor shows a current response of 5.74 decades per pH for pH detection, which is 2.5 105 times larger than that of a single SiNW sensor. In addition, we demonstrate charged polymer detection using the biosensor, with a high current change of 4.5 105 with a 500 nM concentration of poly(allylamine hydrochloride).In addition, we demonstrate a wide dynamic range can be obtained by adjusting the liquid gate voltage. We expect that this biosensor will be advantageous and practical for biosensor applications which requires lower noise, high speed, and high density.

Descriptors :   biosensors , nanowires , METALOXIDE SEMICONDUCTOR FIELDEFFECT TRANSISTOR , detection , amplifiers , dynamic range

Subject Categories : Electrical and Electronic Equipment

Distribution Statement : APPROVED FOR PUBLIC RELEASE