Accession Number : AD1013614

Title :   Effectiveness and Patient Acceptability of Stellate Ganglion Block (SGB) for Treatment of Posttraumatic Stress Disorder (PTSD) Symptoms Among Active Duty Military Members

Descriptive Note : Technical Report,01 Mar 2015,29 Feb 2016

Corporate Author : Research Triangle Institute Research Triangle Park United States

Personal Author(s) : Walters,Bradford B

Full Text :

Report Date : 01 Mar 2016

Pagination or Media Count : 63

Abstract : This study seeks to evaluate the effectiveness and acceptability of stellate ganglion block (SGB) for treatment of Posttraumatic Stress Disorder (PTSD) symptoms. We will conduct two parallel studies: a randomized, controlled trial (RCT) to evaluate the effectiveness of SGB for treating PTSD, and a qualitative study to determine the degree to which the procedure is deemed acceptable by active duty service members with PTSD, their spouses, and their providers. A total of 240 individuals will be enrolled for the RCT portion of the study; qualitative study participants will be convenience sampled from among the RCT participants. For the RCT study, participants will be randomized 2:1 active (SGB) to sham across three study sites. Participants will receive the study condition (active or sham) at weeks 0 (baseline) and 2, and assessments will be conducted at weeks 0, 2, 4, 6, and 8. For the qualitative study, individuals enrolled in the RCT will be asked to participate either in a focus group or an interview with their spouse. In addition, we will conduct focus groups and key informant interviews with providers: those who refer individuals to the study, and those who provide SGB to service members.

Descriptors :   TRAUMATIC STRESS DISORDER , Military personnel , Active duty , Injections(Medicine) , drug therapy , therapeutics , Qualitative analysis , Clinical trials

Distribution Statement : APPROVED FOR PUBLIC RELEASE