Accession Number : AD1012900


Title :   Effect of Solid Lipid Nanoparticle-Encapsulated Antimicrobial Peptide on Keratinocyte Migration and Wound Healing


Descriptive Note : Technical Report


Corporate Author : Uniformed Services University of The Health Sciences Bethesda United States


Personal Author(s) : Caldon,Nathaniel B


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/1012900.pdf


Report Date : 03 May 2013


Pagination or Media Count : 83


Abstract : Objective: This study evaluated the effect of various drug delivery formulations on human keratinocyte migration and viability following treatment with the synthetic antimicrobial peptide KSL-W alone, KSL-W encapsulated in solid lipid nanoparticle (KSL-W + SLN), or solid lipid nanoparticles (SLN) alone evaluated by electric cell substrate impedance sensing (ECIS) (Applied Biophysics), photographic analysis and cell viability.


Descriptors :   WOUNDS AND INJURIES , PEPTIDES , Therapy , ANTIINFECTIVE AGENTS , ORAL HEALTH , LIPIDS


Subject Categories : Medicine and Medical Research
      Pharmacology


Distribution Statement : APPROVED FOR PUBLIC RELEASE