Accession Number : AD1012542

Title :   Genetic Characterization of Spondweni and Zika Viruses and Susceptibility of Geographically Distinct Strains of Aedes aegypti, Aedes albopictus, and Culex quinquefasciatus (Diptera: Culicidae) to Spondweni Virus

Descriptive Note : Journal Article

Corporate Author : USAMRIID Frederick United States

Personal Author(s) : Haddow, Andrew D ; Nasar,Farooq ; Guzman,Hilda ; Ponlawat,Alongkot ; Jarman,Richard G ; Tesh,Robert B ; Weaver,Scott C

Full Text :

Report Date : 26 Oct 2016

Pagination or Media Count : 26

Abstract : Zika virus (ZIKV) has extended its known geographic distribution to the Western Hemisphere and is now responsible for severe clinical complications in a sub-set of patients. While substantial genetic and vector susceptibility data exist for ZIKV, less is known for its sister flavivirus, Spondweni virus (SPONV). Both ZIKV and SPONV have been known to circulate in Africa since the mid-1900s, but neither has been genetically characterized by gene and compared in parallel. Furthermore, the susceptibility of cosmopolitan mosquito species incriminated or suspected in the transmission of ZIKV to SPONV was unknown.

Descriptors :   viruses , infectious diseases , genetics , geographic distribution

Distribution Statement : APPROVED FOR PUBLIC RELEASE