Accession Number : AD1004926


Title :   Identifying Immune Drivers of Gulf War Illness Using a Novel Daily Sampling Approach


Descriptive Note : Technical Report,30 Sep 2014,29 Sep 2015


Corporate Author : University of Alabama - Birmingham Birmingham United States


Personal Author(s) : Younger,Jarred ; Parkitny,Luke ; Smoot,Lisa


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/1004926.pdf


Report Date : 01 Oct 2015


Pagination or Media Count : 19


Abstract : The major aim of this research project is to identify aspects of the immune system that are dysregulated in veterans with Gulf War Illness. A second aim is to determine whether identified immune system dysregulations are similar to those found in men with fibromyalgia. To accomplish those aims at UAB, we are recruiting 29 male veterans diagnosed with Gulf War Illness (GWI), as well as 2 healthy veteran controls, and 4 males with Fibromyalgia/Chronic Fatigue Syndrome (FM/CFS). Participants will complete 25 consecutive days of blood draws and provide daily reports of symptom severity. Analyses will then be conducted to identify immune system factors that correlate with day-to-day symptom fluctuations in the participants. Ultimately,this information may be used to develop new treatments that specifically target the pathophysiological mechanisms of Gulf War Illness.


Descriptors :   Persian Gulf syndrome , Cytokines , Immunity , CHRONIC FATIGUE SYNDROME , IMMUNE SYSTEM DISEASES , therapeutics


Distribution Statement : APPROVED FOR PUBLIC RELEASE