Accession Number : AD1004075

Title :   Biomarkers for Autism and for Gastrointestinal and Sleep Problems in Autism

Descriptive Note : Technical Report,30 Sep 2014,29 Sep 2015

Corporate Author : Yale University New Haven United States

Personal Author(s) : Anderson,George M

Full Text :

Report Date : 01 Dec 2015

Pagination or Media Count : 13

Abstract : The nighttime and daytime excretions of melatonin sulfate were not significantly different between typically developing (TD) toddlers and toddlers with autism spectrum disorders(ASDs). Sleep and gastrointestinal(GI)problems were not associated with lower melatonin excretion in TD or ASD toddlers and to a large extent these problems occurred at similar rates in the TD and ASD groups. The expected day-night differences in melatonin sulfate excretion, and in norepinephrine and epinephrine excretion, were seen in both groups. Thus, the lower melatonin production reported for older children with ASD does not appear to occur in toddlers with ASD.


Distribution Statement : APPROVED FOR PUBLIC RELEASE