Accession Number : AD1001090

Title :   Purification Efficacy of Synthetic Cannabinoid Conjugates Using High-Pressure Liquid Chromatography

Descriptive Note : Technical Report,01 May 2014,01 Aug 2014

Corporate Author : US Army Research Laboratory Aberdeen Proving Ground, United States

Personal Author(s) : Fakner, Alexis M ; West,Abby L ; Karna,Shashi P ; Griep,Mark H

Full Text :

Report Date : 01 Jan 2016

Pagination or Media Count : 28

Abstract : In the current study, we successfully purified several synthetic cannabinoid (SC): dark quencher conjugates essential for the success of the synthetic cannabinoid detection platform developed at the US Army Research Laboratorys Weapons and Materials Research Directorate. The purification was conducted using high-pressure liquid chromatography and gradient screens to determine the most effective means of purifying the SC:dark quencher conjugates to obtain the highest yields and purity. The purity was verified using liquid chromatographycoupled mass spectroscopy and nuclear magnetic resonance.

Descriptors :   detectors , biosensors , advanced oxidation processes , cannabis , liquid chromatography

Subject Categories : Physical Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE