Accession Number : AD0477335


Title :   AN EVALUATION OF RESERPINE THERAPY IN EXPERIMENTAL CEREBRAL EDEMA,


Corporate Author : PRESBYTERIAN-ST LUKE'S HOSPITAL CHICAGO IL


Personal Author(s) : Clasen, Raymond A ; Pandolfi, Sylvia ; Oelke, David ; Hass, George M


Report Date : Oct 1965


Pagination or Media Count : 19


Abstract : Focal areas of hemorrhagic necrosis were produced in the brains of anesthetized monkeys. The animals were followed for a period of 24 hours, after which they were sacrificed and the cerebral hemispheres analyzed chemically for their electrolyte and water content. A second group of animals was treated with reserpine beginning 1 hour after injury. No unequivocal evidence that this form of therapy reduced the edema associated with these lesions was obtained. (Author)


Descriptors :   *NERVOUS SYSTEM DISEASES , *RESERPINE , CEREBRAL CORTEX , EDEMA , CHEMOTHERAPY , NEOPLASMS , ELECTROLYTES(PHYSIOLOGY) , CORRELATION TECHNIQUES , BLOOD ANALYSIS , METABOLISM , EXPERIMENTAL DATA , FREEZING , HEMORRHAGE , PATHOLOGY , PHARMACOLOGY , MONKEYS


Subject Categories : Medicine and Medical Research
      Pharmacology


Distribution Statement : APPROVED FOR PUBLIC RELEASE