Accession Number : AD0474338


Title :   STUDIES ON THE USE OF LIVE ADENOVIRUS VACCINES IN NAVAL RECRUITS.


Descriptive Note : Annual rept. 1 Nov 64-31 Oct 65,


Corporate Author : NAVAL MEDICAL RESEARCH UNIT NO 4 GREAT LAKES IL


Personal Author(s) : Peckinpaugh, R O


Report Date : 31 Oct 1965


Pagination or Media Count : 53


Abstract : Studies were carried out comparing the effect of live oral monovalent adenovirus Type 4 (LAV) in enteric-coated capsules with inactivated vaccines (IAV) on the prevention of such diseases. All of the vaccines were effective in reducing Acute Respiratory Disease hospitalization by the 11th day after vaccination. All were about equally effective in reducting these admissions by 50%. The determination of the exact specific protective effect afforded by these vaccines was confounded by the presence of other etiological agents in the population, including influenza A2. None of the vaccines had any appreciable affect on Acute Respiratory Disease that did not require hospitalization. (Author)


Descriptors :   *VACCINES , *ACUTE RESPIRATORY DISEASE VIRUS , NAVAL PERSONNEL , ANTIGENS , ANTIBODIES , BLOOD ANALYSIS , EXCRETION , TISSUE CULTURE CELLS , SENSITIVITY , INFECTIOUS DISEASES , STATISTICAL DATA , TEST METHODS , INFLUENZA VIRUS , SAMPLING


Subject Categories : Microbiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE