Accession Number : AD0467682


Title :   FETAL LIVER AND THYMUS: ROLES IN THE ONTOGENESIS OF THE MOUSE IMMUNE SYSTEM,


Corporate Author : NAVAL RADIOLOGICAL DEFENSE LAB SAN FRANCISCO CA


Personal Author(s) : Tyan, Marvin L ; Cole, Leonard J


Report Date : 21 Jun 1965


Pagination or Media Count : 8


Abstract : Liver cells or thymic grafts from homozygous embryonic mice were subjected to passage through appropriate nonoperated or thymectomized adult F1 hybrids. Passage through a nonthymectomized host was required for maturation of potential immunologically competent cells derived from embryonic liver; this was not true with regard to cells derived from a fetal thymic graft. Cells from embryonic liver were found first in the host thymus while those from thymic grafts appeared to migrate exclusively to peripheral lymphoid tissues. (Author)


Descriptors :   TRANSPLANTATION , IMMUNOLOGY , CELLS(BIOLOGY) , LIVER , THYMUS , EMBRYOS , RADIATION EFFECTS , EXCISION , ANTIGENS , ANTIBODIES , IMMUNITY , MICE , PHYSIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE