Accession Number : AD0465885


Title :   SUSCEPTIBILITY TO INFECTION IN IRRADIATED ANIMALS


Descriptive Note : Annual rept., 1 Jul 1964-30 Jun 1965


Corporate Author : IIT RESEARCH INST CHICAGO IL


Personal Author(s) : Mieszkuc, Bernard J ; Shefner, Alan M


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/465885.pdf


Report Date : Jun 1965


Pagination or Media Count : 32


Abstract : Exposure of Swiss albino mice to various levels of Co60 gamma radiation and subsequently to various levels of infection with virulent and avirulent strains of Bacillus anthracis indicates that a significant pronounced combined effect is present. At low levels of radiation, bacterial challenges near the LD50 are necessary to demonstrate the combined effect while at high levels of radiation a few organisms produce a pronounced combined effect. The time interval between radiation and infectious challenge significantly affects the degree of interaction with a 7 day interval resulting in higher mortalities than either a 1 or 3 day interval.


Descriptors :   *INFECTIOUS DISEASES , *RADIATION EFFECTS , STATISTICAL DATA , SENSITIVITY , GAMMA RAYS , MICE , SURVIVAL(PERSONNEL) , RADIATION DOSAGE , RADIOBIOLOGY , BACILLUS ANTHRACIS


Subject Categories : Radiobiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE