Accession Number : AD0459386


Title :   9-AMINOACRIDINE BINDING TO DEOXYRIBONUCLEIC ACID: A FLUOROMETRIC ANALYSIS


Descriptive Note : Technical manu.


Corporate Author : ARMY BIOLOGICAL LABS FREDERICK MD


Personal Author(s) : Boyle, Robert E


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/459386.pdf


Report Date : Mar 1965


Pagination or Media Count : 13


Abstract : By using fluorescence quenching and a modification of a spectrophotometric calculation, the number of binding sites for 9-aminoacridine on deoxyribonucleic acid was determined to be 650. That number remained constant although the intrinsic association constant varied from 7.0 x ten to the 6th power to 0.17 x 10 to the 6th power as a function of ionic strength, pH, and dye concentration.


Descriptors :   *CHEMICAL ANALYSIS , *ACRIDINES , IONS , BIOCHEMISTRY , POLYMERIZATION , CHEMICAL BONDS , SURFACE PROPERTIES , DYES , FLUOROMETERS , MOLECULAR PROPERTIES , PH FACTOR , SPECTROPHOTOMETRY


Subject Categories : Biochemistry


Distribution Statement : APPROVED FOR PUBLIC RELEASE