Accession Number : AD0456681


Title :   FLUORESCENT CELL-COUNTING NEUTRALIZATION TEST FOR PSITTACOSIS


Corporate Author : ARMY BIOLOGICAL LABS FREDERICK MD


Personal Author(s) : Hahon, Nicholas ; Cooke, Kenneth O


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/456681.pdf


Report Date : Dec 1964


Pagination or Media Count : 22


Abstract : A sensitive, precise, and specific serological procedure, the fluorescent cell-counting neutralization test, was developed to detect and to measure quantitatively psittacosis serum neutralizing antibodies within 24 hours. The test is based on the reduction of fluorescent cells in McCoy cell monolayers resulting from the neutralization of infective virus particles by specific antiserum. Small but significant rises in neutralizing titers were measured in serum specimens from monkeys previously exposed to the virus and from humans with diagnoses of subclinical or established infections of psittacosis.


Descriptors :   *IMMUNE SERUMS , *FLUORESCENT ANTIBODY TECHNIQUES , *MIYAGAWANELLA PSITTACI , FLUORESCENCE , NEUTRALIZATION , COUNTING METHODS , DIAGNOSTIC AGENTS , AGGLUTININS


Subject Categories : Microbiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE