Accession Number : AD0455125


Title :   MONO- AND POLYNUCLEAR FERRIC NUCLEOTIDES. II. REACTIONS OF FERRIC IRON WITH ADENOSINE AND ADENOSINE PHOSPHATES,


Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY


Personal Author(s) : Goucher, Charles R ; Strickland, E Hardin


Report Date : 20 Jul 1964


Pagination or Media Count : 21


Abstract : The formation and physical properties of monoand polynuclear ferric nucleotides have been investigated. The ferric nucleotide chelates are readily formed in an alkaline medium. One mole of nucleotide can solubilize as many as four gram atoms of ferric iron in the pH range of 7 to 11. Titration curves provided additional evidence for a reaction between iron and nucleotides. The ferric nucleotides have the same pK values for the secondary hydrogen on the terminal phosphate as do the corresponding sodium nucleotides. The possible structures of ferric nucleotides are discussed briefly. (Author)


Descriptors :   *ADENOSINE PHOSPHATES , *NUCLEOTIDES , BIOCHEMISTRY , IRON COMPOUNDS , MOLECULAR PROPERTIES , CHEMICAL REACTIONS , STABILITY , PH FACTOR , NUCLEOTIDES , NUCLEOSIDES , MOLECULAR STRUCTURE , IONS , HYDROXIDES , ORGANOMETALLIC COMPOUNDS


Distribution Statement : APPROVED FOR PUBLIC RELEASE