Accession Number : AD0454818


Title :   THE STRUCTURE OF INDACONITINE,


Corporate Author : NATIONAL RESEARCH COUNCIL OF CANADA OTTAWA (ONTARIO) DIV OF PURE CHEMISTRY


Personal Author(s) : Gilman,Robert E ; Marion,Leo


Report Date : 14 Aug 1964


Pagination or Media Count : 5


Abstract : The alkaloid indaconitine has been converted into delphinine by replacement of a secondary hydroxyl by hydrogen and substitution of an imino-methyl for the imino-ethyl group originally present. This correlation rigorously establishes the structure of indaconitine and its absolute configuration. The product of the saponification of indaconitine, pseudaconitine, pseudaconine, is identical with the product of the saponification of pseudaconitine, and this last alkaloid has been correlated previously with aconitine. It follows that the secondary hydroxyl which was removed in the conversion of indaconitine to delphinine has the same configuration as in aconitine. (Author)


Descriptors :   *ALKALOIDS , MOLECULAR STRUCTURE , STEREOCHEMISTRY , CHROMATOGRAPHIC ANALYSIS , INFRARED SPECTRA , NUCLEAR MAGNETIC RESONANCE , X RAY DIFFRACTION , CANADA


Distribution Statement : APPROVED FOR PUBLIC RELEASE