Accession Number : AD0444571


Title :   Concerning the Influence of Head Irradiation on the Development of Radiation Damage in the Rat Thymus,


Corporate Author : DEFENCE CHEMICAL BIOLOGICAL AND RADIATION LABS OTTAWA (ONTARIO)


Personal Author(s) : Scaife,J F


Report Date : 04 Nov 1963


Pagination or Media Count : 7


Abstract : Early radiation damage in rat thymocytes has been assessed at 4 hours and 24 hours following varying doses of whole body irradiation and compared with the effects produced by a dose of 1000 rads to the head only of the animal. The indirect dose to the shielded thymus in these head irradiation experiments was found to be 22 rads. Adrenalectomized and hypophysectomized animals showed no difference in their response to whole body irradiation as compared to unoperated controls. It is concluded that the adenohypophysis response of irradiation is not involved in the death or damage of thymocytes following low doses of whole body irradiation. (Author)


Descriptors :   *PARTIAL BODY IRRADIATION , RADIATION EFFECTS , THYMUS , CELLS(BIOLOGY) , BIOCHEMISTRY , MORPHOLOGY(BIOLOGY) , RADIATION DOSAGE , RATS


Distribution Statement : APPROVED FOR PUBLIC RELEASE