Accession Number : AD0441231


Title :   DETERMINATION OF HYDRAZINE AND 1-METHYLHYDRAZINE IN BLOOD SERUM.


Descriptive Note : Rept. for Jun 62-Aug 63,


Corporate Author : AIR FORCE AEROSPACE MEDICAL RESEARCH LAB WRIGHT-PATTERSON AFB OH


Personal Author(s) : Reynolds, Barbara A ; Thomas, Anthony A


Report Date : Apr 1964


Pagination or Media Count : 11


Abstract : A simple procedure is described for measuring microgram amounts of hydrazine in the blood serum of rats. The procedure, with a minor modification, can be used for measuring microgram amounts of 1-methylhydrazine. The report presents calibration ranges of 0.5-5.0 micrograms/ml and 0.5-10.0 micrograms/ml of hydrazine and 1-methylhydrazine, respectively. Data are presented on the dose-blood-level relationship of hydrazine and 1-methylhydrazine in rats following intraperitoneal injection. Minimum detectable dose levels were 0.6 mg/kg and 3.0 mg/kg of hydrazine and 1-methylhydrazine, respectively. (Author)


Descriptors :   *BLOOD SERUM , *BLOOD CHEMISTRY , CHEMISTRY , METHYL HYDRAZINES , MEASUREMENT , RATS , CHEMICAL ANALYSIS


Distribution Statement : APPROVED FOR PUBLIC RELEASE