Accession Number : AD0435776


Title :   CUTANEOUS TOXICITY EVALUATION OF AIR FORCE DEVELOPMENT MATERIALS-VI


Descriptive Note : Rept. for Oct 1962-Jan 1964


Corporate Author : INDUSTRIAL BIOLOGY RESEARCH AND TESTING LABS INC PHILADELPHIA PA


Personal Author(s) : Shelanski, Morris V


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/435776.pdf


Report Date : Feb 1964


Pagination or Media Count : 16


Abstract : Ten Air Force development materials were studied via the prophetic patch test method on laboratory animals to determine the primary irritant effect, gross sensitization index, and gross percutaneous toxicity of these materials. The patch test studies with rabbits indicated that three of the materials showed very mild primary irritant action. None of the materials produced any sensitization or gross systemic poisoning. Dermal reactions on rabbits were so mild that testing on humans was not precluded. The materials were, therefore, tested on human volunteers by the Shelanski repeated insult patch test. Results of this test indicated that all of the materials were safe to use on contact with human skin.


Descriptors :   *TOXICITY , *PROPELLANTS , *SKIN(ANATOMY) , HAZARDS , CHEMICAL COMPOUNDS , TOXIC TOLERANCES , AIR , SENSITIVITY , MATERIALS


Subject Categories : Toxicology
      Rocket Propellants


Distribution Statement : APPROVED FOR PUBLIC RELEASE