Accession Number : AD0434459


Title :   BASIC STUDIES IN PERCUTANEOUS ABSORPTION


Descriptive Note : Semi-annual rept. no. 6, Jul-Dec 1963


Corporate Author : LEVER BROS CO EDGEWATER NJ


Personal Author(s) : Vinson, Leonard J ; Koehler, Walter R ; Masurat, Thomas ; Singer, Edward J


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/434459.pdf


Report Date : Dec 1963


Pagination or Media Count : 146


Abstract : Apparatus and techniques have been developed to measure vapor diffusion of chemicals through separated epidermis. The penetration of alcohols and amines has been investigated by this method. Another new technique developed for investigating the penetration of simple agents through skin is that of electrodialysis, which has permitted the study of ionic species which do not normally penetrate skin. A new technique for use in gas chromatographic analysis of fatty acids has also been developed.


Descriptors :   *SKIN(ANATOMY) , *TRANSDERMAL ABSORPTION , PERMEABILITY , VAPORS , ELECTRICAL CONDUCTIVITY , AMINES , PENETRATION , DIFFUSION , ALCOHOLS , LABORATORY ANIMALS , FATTY ACIDS , SILICIC ACIDS , LINOLENIC ACID , ELECTRODIALYSIS


Subject Categories : Pharmacology


Distribution Statement : APPROVED FOR PUBLIC RELEASE