Accession Number : AD0432433


Title :   MYOCARDITIS IN NORMAL RHESUS (MACACA MULATTA) MONKEYS


Corporate Author : ARMY BIOLOGICAL LABS FREDERICK MD


Personal Author(s) : Soto, Peter J , Jr ; Beall, Francis A ; Nakamura, Robert M ; Kupferberg, Lazarus L


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/432433.pdf


Report Date : Feb 1964


Pagination or Media Count : 22


Abstract : A clinical-pathological study was undertaken to ascertain the etiology of myocarditis seen in 18 of 20 normal rhesus monkeys. The results of this study indicate that the myocarditis is not due to a virus that kills suckling mice, nor to bacteria. Moreover, viral inclusion bodies or parasites were not demonstrated morphologically in the myocardium. The myocarditis is most probably idiopathic. Inclusion bodies of salivary gland virus localized to the kidneys of 6 of the 20 monkeys have been described. The significance of slightly elevated SGOT and SGPT values and the presence and significance of multinucleated hepatic parenchymal cells are discussed. Additional hematological and clinical chemistry values are recorded, as are both gross and microscopic anatomical data.


Descriptors :   *MEDICAL RESEARCH , *MYOCARDIUM , TISSUES(BIOLOGY) , BACTERIA , DISEASES , HEART , HEMATOLOGY , ELECTROCARDIOGRAPHY , HISTOLOGY , VIRUSES , PATHOLOGY , PRIMATES


Subject Categories : Anatomy and Physiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE