Accession Number : AD0431218


Title :   LETHALITY OF PENTABORANE-9 IN MAMMALIAN ANIMALS


Descriptive Note : Rept. for 1 June 1962-31 May 1963


Corporate Author : OREGON STATE UNIV CORVALLIS


Personal Author(s) : Dost, F N ; Reed, D J ; Wang, C H


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/431218.pdf


Report Date : Dec 1963


Pagination or Media Count : 17


Abstract : A method of transfer and administration of pentaborane-9 to small animals was described. By use of this procedure, median lethal doses of pentaborane-9 by intraperitoneal and inalation administration to the rat were determined to be 3.7 mg/kg and 0.42 mg/kg respectively. An antravenous median lethal dose to the rabbit of 0.52 mg/kg was estimated. The suggestion was made that pentaborane-9 does not oxidize appreciably prior to inhalation, and was almost quanitatively removed from respired air.


Descriptors :   *TOXICITY , *PENTABORANES , MAMMALS , DRUGS , LABORATORY ANIMALS , BOROHYDRIDES , LETHAL DOSAGE , RATS


Subject Categories : Toxicology
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Distribution Statement : APPROVED FOR PUBLIC RELEASE