Accession Number : AD0163558


Title :   Method of Synthesizing Selenoureas from Thioureas.


Descriptive Note : Patent,


Corporate Author : OFFICE OF THE SECRETARY OF THE ARMY WASHINGTON D C


Personal Author(s) : Klayman,Daniel L. ; Shine,Robert J.


Report Date : 03 AUG 1971


Pagination or Media Count : 2


Abstract : The patent relates to the preparation of selenoureas having either aliphatic or aromatic substituents by displacement of the thiomethyl moiety from S-methylthiopseudoureas by hydroselenide ions in solutions having a pH of 8 to 9. This method provides yields of substituted selenoureas in the range of 60-70 percent. Selenoureas are useful in synthesizing a wide variety of seleno substituted compounds, for example the seleno substituted steroids. (Modified author abstract)


Descriptors :   (*PATENTS, UREA), (*UREA, SYNTHESIS(CHEMISTRY)), SELENIUM COMPOUNDS, STEROIDS, DRUGS


Subject Categories : PHARMACOLOGY
      ORGANIC CHEMISTRY


Distribution Statement : APPROVED FOR PUBLIC RELEASE