Accession Number : AD0015676


Title :   AN IMMUNOLOGICAL INVESTIGATION OF THE HERPES SIMPLEX VIRUS


Descriptive Note : Semi-annual progres rept. no. 4, 1 Jan-30 Jun 1953


Corporate Author : GEORGE WASHINGTON UNIV WASHINGTON DC


Personal Author(s) : Robbins, Mary L


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/015676.pdf


Report Date : 31 Jul 1953


Pagination or Media Count : 5


Abstract : Cross-complement fixation tests indicated slight differences in the titer of hyperimmune guinea pig sera against LF, Z, and EB strains of the Herpes simplex virus. Human sere showed marked differences among these 3 and 5 other strains. Hyperimmune guinea pig sera were adsorbed with crude infective mouse- brain suspensions and tested for neutralizing antibodies in mice and chick embryos. Neutralizing antibodies were removed or greatly reduced, and no antigenic differences were indicated among the 3 strains.


Descriptors :   *HERPES SIMPLEX VIRUS , ANTIBODIES , IMMUNE SERUMS , CHICKENS , EMBRYOS , GUINEA PIGS , NEUTRALIZATION , MICE


Subject Categories : Microbiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE