Accession Number : AD0005468


Title :   STUDIES ON THE PROTECTIVE ACTION OF SULFHYDRYL COMPOUNDS AGAINST X- IRRADIATION


Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY


Personal Author(s) : PARR, W ; PUCKETT, N ; RANSOM, R ; SPRADLING, S ; KREBS, A


Full Text : https://apps.dtic.mil/dtic/tr/fulltext/u2/005468.pdf


Report Date : 12 Nov 1952


Pagination or Media Count : 18


Abstract : Cysteine, in a concentration of 850 mg/kg body weight administered intravenously 10 min prior to total body irradiation with 880 r, counteracted the inhibiting effect of x-rays on nucleic acid synthesis in the intestinal mucosa of the albino rat. Immediately after irradiation the rats received 20-50 micro-c P to the power of 32 intraperitoneally. The small intestine was used for determining the inorganic tissue P and desoxypentose nucleic acid P and their specific activities.


Descriptors :   *BIOSYNTHESIS , *RADIATION SHIELDING , RATS , IRRADIATION , INTESTINES , CYSTEINE , MUCOUS MEMBRANES , NUCLEIC ACIDS , ALBINISM , SMALL INTESTINE


Subject Categories : Nuclear Radiation Shield, Protection & Safety


Distribution Statement : APPROVED FOR PUBLIC RELEASE