Accession Number : AD0002588
Title : The Effects of Ethyl Alcohol of The Brain
Descriptive Note : Research rept.
Corporate Author : EMORY UNIV ATLANTA GA SCHOOL OF MEDICINE
Report Date : 10 Oct 1952
Pagination or Media Count : 17
Abstract : The cerebral blood flow (CBF), cerebral metabolism (CMRO sub2), and vascular resistance (CVR) were measured in 15 subjects before and during intravenous administration of EtOH, and in 12 patients during severe alcoholic intoxication and following recovery. EtOH doses sufficient to produce facial vasodilatation and mild intoxication (about 68 mg-% alcohol concentration in the blood) did not affect the CBF, CMRO sub 2, or CVR. During acute alcoholic intoxication (about 320 mg-% alcohol concentration), there was a marked increase in mean CBF and a significant reduction in CMRO sub 2 and CVR, as compared with the values after recovery.
Descriptors : *CEREBRUM , *INTOXICATION , *ALCOHOL CONSUMPTION , HIGH RATE , METABOLISM , DOSAGE , CARDIOVASCULAR SYSTEM , BLOOD CIRCULATION , RESISTANCE(BIOLOGY) , ALCOHOLISM
Subject Categories : Biochemistry
Distribution Statement : APPROVED FOR PUBLIC RELEASE